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翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Combinatorial biology ： ウィキペディア英語版 Combinatorial biology In biotechnology, combinatorial biology is the creation of a large number of compounds (usually proteins or peptides) through technologies such as phage display. Similar to combinatorial chemistry, compounds are produced by biosynthesis rather than organic chemistry. This process was developed independently by Richard A. Houghten and H. Mario Geysen in the 1980s. Combinatorial biology allows the generation and selection of the large number of ligands for high-throughput screening.〔 〕〔 〕 These large numbers of peptides are generated and screened by physically linking a gene encoding a protein and a copy of this protein. This could involve the protein being fused to the M13 minor coat protein pIII, with the gene encoding this protein being held within the phage particle. Large libraries of phages with different proteins on their surfaces can then be screened through automated selection and amplification for a protein that binds tightly to a particular target. == Notes == 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Combinatorial biology」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.